REF CANCER
CANCER – BRCA GENE - BREAST CANCER
CHILDHOOD CANCER - COLON CANCER
MELANOMA
Cancer is a group of diseases involving abnormal cell growth and can spread throughout your body. It is the second-leading cause of death in the world after cardiovascular diseases.
Note: There is nothing in the book “The Miracle of MSM” about any clinical experiences with cancer patients. I suspect that no one has ever considered going to Dr. Jacob’s clinic for this type of medical disorder. In 1986, Dr. Jacob’s faculty members performed a few mice laboratory experiments and found that MSM had some surprising cancer reversing effect on mice.
Below, I report some published peer reviewed studies showing that MSM has autoimmune normalizing properties effective against different cancers, including bladder cancer, breast cancer, colon cancer, gastrointestinal (esophagus, stomach, and liver cancers), hepatic cancer, lung, colorectal, and skin (melanoma) cancers.
As reported on this website, in "MSM'S KNOWN HEALTH BENEFITS", some of the main observations by Dr. Jacob in his medical clinic MSM research and MSM's use as a sulfur nutritional supplement are:
-MSM is an analgesic and relieves pain and inflammation (it has anti-inflammatory properties), this has been corroborated later in many peer reviewed published studies, two of which are shown below,
-MSM has antiparasitic properties,
-MSM has an immune normalizing effect observed in autoimmune diseases. This has been corroborated later in many peer reviewed published studies as shown further below.
Chronic inflammation has been hypothesized to directly cause cancer mutation. Here are two of the many studies in which this has been observed:
Gaeta JF (2000). "Chapter 17: Trauma and Inflammation". In Bast RC, Kufe DW, Pollock RE, et al. (eds.). Holland-Frei Cancer Medicine (5th ed.). Hamilton, Ontario: B.C. Decker. In the following book: ISBN 978-1-55009-113-7.
and in:
Colotta F, Allavena P, Sica A, Garlanda C, Mantovani A (July 2009). "Cancer-related inflammation, the seventh hallmark of cancer: links to genetic instability". Carcinogenesis (review). 30 (7): 1073–81. doi:10.1093/carcin/bgp127.
Published here: https://pubmed.ncbi.nlm.nih.gov/19468060/.
Inflammation can contribute to proliferation, survival, angiogenesis, and migration of cancer cells by influencing the tumor microenvironment. Here are two of the many studies this has been observed in:
Ungefroren H, Sebens S, Seidl D, Lehnert H, Hass R (September 2011). "Interaction of tumor cells with the microenvironment".
Cell Communication and Signaling, published here:
and in
Mantovani A (June 2010). "Molecular pathways linking inflammation and cancer". Current Molecular Medicine (review). Published here:
Oncogenes build up an inflammatory pro-tumorigenic microenvironment. Here is one published letter this has been observed in:
Borrello MG, Degl'Innocenti D, Pierotti MA (August 2008). "Inflammation and cancer: the oncogene-driven connection". Cancer Letters (review). 267 (2): 262–70. doi:10.1016/j.canlet.2008.03.060.
Published here: https://pubmed.ncbi.nlm.nih.gov/18502035/
All reported observations above show that cancer is generally related to inflammation which is why many studies show the benefits of MSM’s anti-inflammatory properties to prevent and treat cancer.
In the last twenty-five years, there have been more than twenty-five different peer reviewed medical and biological cancer studies reporting on the benefits of MSM to fight cancer, all published in the public U.S. National Library of Medicine, National Institutes of Health.
Following are two recent peer reviewed published studies on MSM’s cancer benefit:
1.- BREAST CANCER
Here is the summary of a 2012 scientific study that shows the therapeutic properties of MSM in the treatment of breast cancer, a severe inflammatory disease.
Methylsulfonylmethane Suppresses Breast Cancer Growth by Down-Regulating STAT3 and STAT5b Pathways.
Eun Joung Lim, Dae Young Hong, Jin Hee Park, Youn Hee Joung, Pramod Darvin, Sang Yoon Kim, Yoon Mi Na, Tae Sook Hwang, Sang-Kyu Ye, Eon-Soo Moon, Byung Wook Cho, Kyung Do Park, Hak Kyo Lee, Taekyu Park, Young Mok Yang.
Department of Pathology, School of Medicine, and Institute of Biomedical Science and Technology, Konkuk University Glocal Campus, Seoul, South Korea.
Abstract:
Breast cancer is the most aggressive form of all cancers, with high incidence and mortality rates. The purpose of the present study was to investigate the molecular mechanism by which methylsulfonylmethane (MSM) inhibits breast cancer growth in mice xenografts. MSM is an organic sulfur-containing natural compound without any toxicity. In this study, we demonstrated that MSM substantially decreased the viability of human breast cancer cells in a dose-dependent manner. MSM also suppressed the phosphorylation of STAT3, STAT5b, expression of IGF-1R, HIF-1α, VEGF, BrK, and p-IGF-1R and inhibited triple-negative receptor expression in receptor-positive cell lines. Moreover, MSM decreased the DNA-binding activities of STAT5b and STAT3, to the target gene promoters in MDA-MB 231 or co-transfected COS-7 cells. We confirmed that MSM significantly decreased the relative luciferase activities indicating crosstalk between STAT5b/IGF-1R, STAT5b/HSP90α, and STAT3/VEGF. To confirm these findings in vivo, xenografts were established in Balb/c athymic nude mice with MDA-MB 231 cells and MSM was administered for 30 days. Concurring to our in vitro analysis, these xenografts showed decreased expression of STAT3, STAT5b, IGF-1R and VEGF. Through in vitro and in vivo analysis, we confirmed that MSM can effectively regulate multiple targets including STAT3/VEGF and STAT5b/IGF-1R. These are the major molecules involved in tumor development, progression, and metastasis. Thus, we strongly recommend the use of MSM as a trial drug for treating all types of breast cancers including triple-negative cancers.
MY NOTE: The researchers recommendation in the last phrase of the previous paragraph refers to MSM as a trial drug but it is really a natural sulfur nutritional supplement, a treatment agent, and not a drug.
For the whole study go to:
2.- MELANOMA
Here is the summary of a 2010 scientific study that shows the therapeutic properties of MSM in the treatment of melanoma, a severe autoimmune disease. Methyl sulfone is the most common pharmacology name for MSM. Its most technically accurate name is dimethyl sulfone (DMSO2).
My Note: The researchers here refer to MSM as a non-toxic agent.
For the whole study go to:
These studies were performed forty and fifty some years after the start of the study of the importance of MSM in the human body by Dr. Stanley W. Jacob, M.D., and Robert Herchler, chemist, two US scientists, and eleven and nineteen years after the publication of the book “The Miracle of MSM” by Dr. Jacob.
These published peer reviewed studies, just like many others, conclude that MSM renders the cancer cells back to normal cells and prevents the surrounding cells becoming cancerous. THIS IS SOMETHING THAT NO KNOWN CHEMOTHERAPY DRUG CAN DO, AND ABOVE ALL, A FULLY NONTOXIC NATURAL PROCESS WITHOUT SIDE EFFECTS AND THE EXCESSIVE COST OF MEDICINES.
As mentioned above, Dr. Jacob had already discovered the fact that MSM has an anti-inflammation normalizing effect observed by his team in many other inflammatory diseases.
3.- BRCA GENE
This condition is hereditary, and people diagnosed with this condition are usually at higher risk of cancer.
The condition is caused by high penetrance mutations between BRCA1 and BRCA2, two proteins found in breast and other tissue. The mutations cause a loss of tumor suppressive function by these proteins increasing the risk of breast and other cancers.
In women it could lead to higher breast, ovarian, fallopian tube, and pancreatic cancer diagnostic. In men it could lead to higher breast, prostate, and pancreatic cancer diagnostic.
As reported above, MSM has autoimmune normalizing effects at the cell level.
Many women with this condition resort to EARLY mastectomy and hysterectomy to lower their risk of cancer. Why not take the MSM natural sulfur nutritional supplement and see if the tests results are changed after a year or so? One may see a difference much earlier.
Because of MSM's normalizing effects observed in many other proteins imbalance, its proven autoimmune normalizing effects at the cell level as reported above, MSM may modify the mutations between these BRCA proteins.
If I had family cancer history, diagnosed with BRCA, or were diagnosed with any type of cancer, I sure would start taking MSM and slowly increase my intake to the largest dose possible to see if it may help. There is nothing to lose, it is inexpensive, and MSM does not interact with any medication as observed by Dr. Jacob in his more than thirty thousand patients treated with MSM. Just take the MSM sulfur nutritional supplement as an added treatment agent to whatever treatment you already are on.
And to prevent breast cancer, also apply the MSM water based massaging gel or lotion three to four times a day on the breasts. Make sure you massage the MSM until your breast and hand are dry and all the MSM has penetrated your skin. This process provides much more MSM to your breast than the oral intake alone.
4.- COLON CANCER
More young people are getting diagnosed with — and dying from — colon cancer. The proportion of colorectal cancer in people under 55 doubled between 1995 to 2019, from 11% to 20%, per the American Cancer Society, during the same time overall incidence of colon cancer decreased in the US.
Scientists predict the disease will be the leading cause of cancer death among people under 50 by 2030.
Colon cancer has a high survival rate when caught early, but young people typically are not diagnosed until the disease has reached an advanced stage: over half of people under 50 receive a diagnosis at stage three or four, compared to just 40% of people over 50 diagnosed at those later stages.
5.- CHILDHOOD CANCER
As of 2014, according to the American Childhood Cancer Organization, each year in the U.S. there are an estimated 15,780 children between the ages of birth and 19 years of age who are diagnosed with cancer. And 12.4% of these children die making cancer the leading cause of death of children. Approximately 1 in 285 children in the U.S. will be diagnosed with cancer before their 20th birthday. Globally there are more than 300,000 children diagnosed with cancer each year.
A 2023 JAMA Pediatrics analysis of several studies found that children, adolescent, and young adult cancer survivors have an increased risk of depression, anxiety, and psychotic disorders after going into remission compared with siblings and peers who never had cancer.
If diagnosed with any type of cancer, consult with your physician and if he or she does not know about MSM, have him or her read the books “The Miracle of MSM” and “MSM the definitive guide,” the second book for medical professionals. Your physician can also read this website and all the peer reviewed published MSM medical studies including the two above, part of over twenty-five cancer studies, in the U.S. National Library of Medicine, National Center for Biotechnology Information.
SUMMARY
As a summary of what we read on cancer in this section, if one has a family cancer history, diagnosed with BRCA, or were diagnosed with any type of cancer, why not start taking MSM and slowly increase its intake to the largest dose possible to see if it may help. There is nothing to lose, it is inexpensive, and MSM does not interact with any medication as observed by Dr. Jacob in his more than thirty thousand patients treated with MSM. Just take the MSM sulfur nutritional supplement as an added treatment agent to whatever treatment you already are on. You and your doctor may be happily surprised.
In most health disorders, the suggested dosage is 2,000 to 8,000 mg of MSM daily in the form of crystals or capsules to help give more flexibility to the muscles and reduce the pain in the joints. Dr. Jacob recommends starting with the smaller dose and increasing gradually by taking the MSM dose in your daily fluid intake. Because MSM is known to increase energy level, Dr. Jacob recommends not to take it near bedtime.
One should also use the MSM topical massaging gel, a few times a day, on any affected skin area and any of the muscles and joints giving pain.
Whether or not you have a family history of cancer like me, my mom died of leukemia, is it not worth spending $10 to $40 a month on MSM nutritional supplement to see if one can prevent cancer in a fully nontoxic natural process without medicines side effects and their excessive cost?
IF YOU DO NOT REMEMBER, PLEASE SEE THE LAST PART OF THE SECTION OF THIS WEBSITE THAT TALKS ABOUT “SULFUR IN OUR LIFE” TO UNDERSTAND A LITTLE MORE ABOUT THE INCIDENCE OF CANCER IN THE WORLD. AND ASK YOURSELF WHY IS IT THAT FROM 1990 TO 2017, THE DEATH RATE FROM CANCER INCREASED BY 17% WORLDWIDE AND THE USA HAS ONE OF THE HIGHEST RATES?
IN EVERY DECADE SINCE THEN, THE EARLY-ONSET OF CANCER HAPPENS AT A YOUNGER AGE AND NOW AFFECTS MORE PEOPLE UNDER AGE FIFTY AS REPORTED IN THE FOLLOWING STUDY:
AS FOOD FOR THOUGHT, DON'T YOU BELIEVE LIKE ME THAT THE MEDICAL FIELD HAS A VERY POOR RATE OF SUCCESS WITH CANCER?
Notice: Every time you use the MSM therapeutic topical gel, make sure your hands and the massaged area are clean because the MSM penetrates the skin, and one does not want to infect the skin with dirt. Also make sure that you rub the MSM gel in until your hands and the massaged area are completely dry to avoid the MSM crystals staying on top of your skin when the gel’s water evaporates. The demineralized water-based gel contains 15% MSM, which is the maximum to avoid crystallization. So, to prevent the MSM from crystallizing in the MSM gel bottle, do not forget to close the MSM gel bottle lid after use.
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